When there is moisture,Website:http://www.dlskychem.com, it will easily react with weak oxidants. Soluble in alcohol, chloroform, benzene and ether, soluble in water. The solubility in water increases with the addition of sodium benzoate. The aqueous solution is weakly alkaline to litmus. The melting point is 107-109 ° C.Melting point107-109 °C(lit.)Boiling point373.38°C (rough estimate)Density1.0744 (rough estimate)Refractive index1.6140 (estimate)Storage conditionsRefrigeratorAcidity coefficient (pKa)pKa 5.0 (Uncertain)formCrystalline Powder, Crystals and/or ChunkscolourOff-white to brownishWater solubility5.55 g/100 mLSensitivityAir & Light SensitiveMerck14,474USEAntipyretic and analgesic for fever, headache, joint pain, neuralgia, dysmenorrhea and active rheumatism. Aminopyrine is a pyrazolone non-steroidal anti-inflammatory drug with strong antipyretic, analgesic, anti-inflammatory and anti-rheumatic effects. However, due to serious adverse reactions, such as agranulocytosis, aplastic anemia and so on. Therefore, the clinical application has been decreasing and gradually phasing out. Aminopyrine can also be used as an analytical reagent for the determination of lanthanum, cerium, bromine, cadmium, chlorine, cobalt, ketone, cyanide, gold, iron iodic acid, lead, nickel, nitric acid, nitrite, bismuth, nitrogen oxides, Palladium, platinum, silver and zinc.